Specific glucocorticoid binding in human hemopoietic cell lines and neoplastic tissue.
نویسندگان
چکیده
cellular macromolecular fractions was studied in three human lymphoid cell lines (HR1K, RPM1 8226, and MOLT-4), in four lymphosarcomatous tumors, and in leukemic leukocytes obtained from the peripheral blood of three patients with acute lymphocytic leukemia, six with acute myelocytic leukemia, eight with chronic lympho cytic leukemia, and two with chronic myelocytic leukemia. Specific binding, which was manifested by a high binding affinity of TA-3H to the macromolecular fractions and by
منابع مشابه
Detection of Her2 Levels in Cancerous Cells Based on Iron Oxide Nanoparticles
In this study, we synthesized Herceptin conjugated magnetic nanoparticles (HMNs) as an alternative probe to discover the levels of HER2 (Human epidermal growth factor receptor-2) in the surface of cells. These nanoparticles can be used by magnetic resonance imaging (MRI) (non-invasive methods) for screening the patients with HER2 positive or negative tumors. Dextran coated iron oxide nanopartic...
متن کاملDetection of Her2 Levels in Cancerous Cells Based on Iron Oxide Nanoparticles
In this study, we synthesized Herceptin conjugated magnetic nanoparticles (HMNs) as an alternative probe to discover the levels of HER2 (Human epidermal growth factor receptor-2) in the surface of cells. These nanoparticles can be used by magnetic resonance imaging (MRI) (non-invasive methods) for screening the patients with HER2 positive or negative tumors. Dextran coated iron oxide nanopartic...
متن کاملPossible Involvement of a Specific Cell Surface Receptor for Calprotectin-Induced Apoptosis in Colon Adenocarcinoma and Carcinam Cell Lines (SW742 and HT29/219)
Calprotectin, a calcium-bound protein complex, is abundant in the cytosol of neutrophils. It has been reported that this protein has an apoptotic activity in tumor cells. Since calprotectin increases in colorectal cancer, this study was conducted to investigate, for the first time, the cytotoxicity/apoptotic effect of calprotectin on HT29/219 and SW742 colon carcinoma and adenocarcinoma cell li...
متن کاملSelective Inhibitory Effect of Adenosine A1 Receptor Agonists on the Proliferation of Human Tumor Cell Lines
Background: In this study, the effects of three structural analogues of adenosine upon proliferation of human tumor cells were investigated. Previous research showed a cytotoxic effect of adenosine via A3 receptor and A1 receptor and sometimes this effect was receptor independent. The researches showed a differential cytotoxic effect of adenosine and its A3 agonists on cancerous cells, while ot...
متن کاملA STUDY ON THE HEMOPOI ETIC ACTIVITY OF HUMAN PLACENTA IN VITRO, IN THE PRESENCE AND ABSENCE OF STIMULATORS AND INHIBITORS OF TRANSCRIPTION AND TRANSLATION
The hemopoietic activity of the human placenta was studied in vitrc under various conditions in order to assess the optimal conditions of protein synthesis and colony stimulating factor (CSF) production by this tissue. The hemopoietic activity of placental tissue was assayed by the semi -solid agar medium technique. In order to obtain maximum hemopoietic activity, various stimulators were ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Cancer research
دوره 33 11 شماره
صفحات -
تاریخ انتشار 1973